Medical applications of neutron inelastic scattering

Joseph J. Kehayias; Anathea Banuk-Waitekus; Silvia Valtuena; Charles A. Sheahan

doi:10.1117/12.363685

1 October 1999 Medical applications of neutron inelastic scattering

Joseph J. Kehayias, Anathea Banuk-Waitekus, Silvia Valtuena, Charles A. Sheahan

Proceedings Volume 3769, Penetrating Radiation Systems and Applications; (1999) https://doi.org/10.1117/12.363685
Event: SPIE's International Symposium on Optical Science, Engineering, and Instrumentation, 1999, Denver, CO, United States

Abstract

A sealed, D-T, pulsed neutron generator is used for the in vivo measurement of body carbon and oxygen by neutron inelastic scattering. The generator is operated at 10 KHz, at a neutron output of about 2 X 10⁷ n/s/4(pi) . Gamma ray spectra are collected with two B₄Ge₃O₁₂ crystal detectors. The measurements are used to measure fat and lean content and distribution in the body, with minimal radiation exposure (0.08 mSv). When combined with other measurements (such as total body potassium), this whole body scanning device provides us with the `quality of lean mass', a measurable outcome of treatments designed to improve nutritional status and function. The method is used in studies of human nutrition and for assessing the efficacy of new anti-obesity and anti-cachexia pharmaceuticals.

Citation Download Citation

Joseph J. Kehayias, Anathea Banuk-Waitekus, Silvia Valtuena, and Charles A. Sheahan "Medical applications of neutron inelastic scattering", Proc. SPIE 3769, Penetrating Radiation Systems and Applications, (1 October 1999); https://doi.org/10.1117/12.363685

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