Experimental assessment of analytical models for estimating tumor optical properties in laser pulse mammography

D. Grosenick; B. Wassermann; R. Macdonald; H. Rinneberg; A. Torricelli; L. Spinelli; R. Cubeddu

doi:10.1117/12.632842

7 October 2005 Experimental assessment of analytical models for estimating tumor optical properties in laser pulse mammography

D. Grosenick, B. Wassermann, R. Macdonald, H. Rinneberg, A. Torricelli, L. Spinelli, R. Cubeddu

Author Affiliations +

Proceedings Volume 5859, Photon Migration and Diffuse-Light Imaging II; 58590M (2005) https://doi.org/10.1117/12.632842
Event: European Conferences on Biomedical Optics 2005, 2005, Munich, Germany

Abstract

We analyzed measured and simulated phantom data for absorption and reduced scattering coefficients of embedded spherical inhomogeneities using various analytical models, based on diffusion theory. The model of diffraction of photon density waves was found to be superior to the empirical, non-linear perturbation model (Pade approximants) whereas linear perturbation theory considerably underestimates absorption in the range of absorption coefficients and spherical volumes most relevant to tumors detected by optical mammography.

Citation Download Citation

D. Grosenick, B. Wassermann, R. Macdonald, H. Rinneberg, A. Torricelli, L. Spinelli, and R. Cubeddu "Experimental assessment of analytical models for estimating tumor optical properties in laser pulse mammography", Proc. SPIE 5859, Photon Migration and Diffuse-Light Imaging II, 58590M (7 October 2005); https://doi.org/10.1117/12.632842

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