Novel fabrication technology of polydimethylsiloxane microfluidic chip

Bo Su; Yanqiu Li; Hongguang Sun

doi:10.1117/12.782732

19 November 2007 Novel fabrication technology of polydimethylsiloxane microfluidic chip

Bo Su, Yanqiu Li, Hongguang Sun

Author Affiliations +

Proceedings Volume 6724, 3rd International Symposium on Advanced Optical Manufacturing and Testing Technologies: Design, Manufacturing, and Testing of Micro- and Nano-Optical Devices and Systems; 672410 (2007) https://doi.org/10.1117/12.782732
Event: 3rd International Symposium on Advanced Optical Manufacturing and Testing Technologies: Large Mirrors and Telescopes, 2007, Chengdu, China

Abstract

The fabrication of PDMS microfluidic chip was reported. The microchip was composed of multimode optical fiber, PDMS cover slab and PDMS base slab. The mould of cover slab was achieved by using twice exposal technology and the microfluidic chip was fabricated with casting PDMS method. The microfluidic channel with a 50μm depth and the fiber channel with a 90μm depth were formed in the PDMS cover slab, and another fiber channel with a 40μm depth were made in the PDMS base slab, so the centers of the microfluidic channel and the fiber could be located in the same plane. Several factors, which affect the characteristic of the chip, were discussed. The experiment was achieved with the fabricated chip to separate Fluorescein Isothiocyanate (FITC) and FITC-labeled amino acid mixture reagent, and the feasibility of the chip was approved.

Citation Download Citation

Bo Su, Yanqiu Li, and Hongguang Sun "Novel fabrication technology of polydimethylsiloxane microfluidic chip", Proc. SPIE 6724, 3rd International Symposium on Advanced Optical Manufacturing and Testing Technologies: Design, Manufacturing, and Testing of Micro- and Nano-Optical Devices and Systems, 672410 (19 November 2007); https://doi.org/10.1117/12.782732

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KEYWORDS

Microfluidics

Light emitting diodes

Light sources

Photoresist materials

Photomasks

Multimode fibers

Biological research

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