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In this work, we used the laser-ablated Titanium Nitride (TiN) nanoparticles as an exogenous contrast agent for lab-made PAM (Photoacoustic Microscopy) and PAT (Photoacoustic Tomography). The absorption spectra of the 50-100 nm-sized TiN nanoparticles confirmed the presence of a broad plasmonic band covering both parts of the visible and near-infrared (NIR) spectrum. The PAM system was used to image the TiN nanoparticles with a resolution of ~ 50 µm, underneath 1 mm chicken breast tissue. For the PAT results, lower resolution (~ 400 µm) was measured, but the penetration depth of 2 cm was observed.
Avishek Das andAnderson S. L. Gomes
"Photoacoustic microscopy and tomography for biomedical imaging with plasmonic TiN nanoparticles", Proc. SPIE PC11990, Nanoscale and Quantum Materials: From Synthesis and Laser Processing to Applications 2022, PC119900H (1 April 2022); https://doi.org/10.1117/12.2615368
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Avishek Das, Anderson S. L. Gomes, "Photoacoustic microscopy and tomography for biomedical imaging with plasmonic TiN nanoparticles," Proc. SPIE PC11990, Nanoscale and Quantum Materials: From Synthesis and Laser Processing to Applications 2022, PC119900H (1 April 2022); https://doi.org/10.1117/12.2615368