The paper is aimed at comparing blood microcirculation parameters of conditionally healthy volunteers and patients undergoing rehabilitation after COVID-19 to identify possible blood flow dysregulation that may result from the disease. A system of wearable laser Doppler monitors was used to conduct the study. The study demonstrated an increase in overall oscillatory blood flow activity in the group of patients compared to the control group, with especially pronounced differences in the neurogenic, respiratory and cardiac ranges. It had been shown that optical non-invasive technologies have the potential for further application in the research related to COVID-19.
The work aims to study the features of autonomic control of the cardiovascular system in two groups of patients with Covid-19: with and without arterial hypertension. A total of 15 pairs of 20-minute electrocardiogram and photoplethysmogram signals were registrated in each group. We used the methods of spectral analysis, as well as the previously proposed method for assessing the phase synchronization of 0.1-Hz rhythms of signals of autonomic control of heart rate and blood pressure. The data of patients with chronic arterial hypertension showed a lower level of synchronization than patients without it. This is probably due to the peculiarities of autonomic control of the cardiovascular system in patients with chronic arterial hypertension.
The possibility of using the laser Doppler flowmetry (LDF) method for the diagnosis of masked hypertension is considered. Significant trends in changes in parameters between groups of volunteers were identified. This indicates the possibility of using the LDF method to make decisions about the further follow-up of patients for the presence of a hidden increase in BP.
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