A probe was developed to detect biomolecular binding events on a substrate in the microwave regime in real time and without labels. The probe consists of a coplanar transmission line fabricated on a glass slide that can detect dielectric changes in close proximity of the substrate-liquid interface. The probe behavior was evaluated by adsorbing polyelectrolyte monolayers of alternating charge. Biomolecular detection was demonstrated by immobilizing protein A on the glass surface and detecting rabbit IgG molecules in a flow channel. The sensitivity of the probe was conservatively estimated to be ~100 pg/mm2.
Howard Abraham, Homer Antoniadis, Daniel Roitman, Kyle Frischknecht, Travis Blalock, Ken Nishimura, Thomas Knotts, Jeremy Theil, Chris Bright, Jeffrey Miller, Ronald Moon
Capable self-emissive polymers are being developed for use as emitting materials for a variety of display applications. This paper describes the use of standard CMOS integrated circuit silicon wafer technology along with a spin-cast polyfluorene-base polymer emissive layer, to demonstrate an XGA resolution, full video microdisplay. The silicon chip drive circuitry (Analog Pixel-APIX) is described along with results from our efforts to optimize the reflective anode, the semitransparent cathode process, and emissive cell construction. The 1024 X 768 pixel display achieves 200 Cd/m2 brightness at low power (<50 mW) with fast 1 usec response times. In addition, we summarize future directions to achieve color and the need to incorporate a production- worthy seal layer on microdisplays manufactured on silicon wafers.
One of the themes that has emerged in the field of organic light emitting devices (OLEDs) is the importance of developing materials that form robust films, capable of undergoing wet and dry processing conditions. It is through such characteristics that polymers may have unique opportunities in the effective and inexpensive study of novel single and double layer thermosetting and solvent soluble polymer light emitting devices based on triarylamines for hole transport layer and compounds possessing the blue emitting 9,9-dialkylfluorene unit for the emitting and electron transport layer. These devices possess high thermal stability, high quantum efficiency, and high bandgap emission. We fabricated dot matrix displays based on analogs of these materials where cathode separation was achieved 'in situ' by a resist structure with reentrant wall profile that was built on top of the EL layers. This is a demonstration that polyfluorenes are robust and compatible with standard resist processing.
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