Dr. Emmanuel Maillart Profile

Dr. Emmanuel Maillart

at Horiba France SAS

SPIE Involvement:

Author

Publications (3)

Proceedings Article | 1 April 2020 Presentation

What can orthogonal surface functionalizations provide to point-of-care testing? (Conference Presentation)

Jian Zhang, Francisco Palazon, Christelle Yeromonahos, Radoslaw Mazurczyk, Thomas Géhin, Claude Botella, Geneviève Grenet, Didier Léonard, Stéphane Monfray, Julien Moreau, Michael Canva, Yann Chevolot, Emmanuel Maillart, Jean-Pierre Cloarec

Proceedings Volume 11361, 1136108 (2020) https://doi.org/10.1117/12.2560154

KEYWORDS: Point-of-care devices, Chemical analysis, Gold, Silica, Biosensors, Transducers, Molecular self-assembly, Titanium, Tungsten, Nanoparticles

Read Abstract +

MicroAnalytical Systems (µAS) adapted to Point-of-Care Testing are expected to provide simple chemical, molecular or cellular analysis to be used directly on the field. Different formats of µAS are already classically used, from pregnancy tests to glycemia for diabetic people. Increasing µAS analytical performances involves for instance improving limits of detection, reduce time of analysis, or increase the amount of information provided per test. These improvements may be reached by using more refined technology, involving integrated technologies such as biosample processing, enzymatic reactions, fluidic circuitry and/or biosensors. However being able to fabricate and produce cheap µAS relying on miniaturized components is still a challenging goal, particularly when dealing with low concentrated species. For example, on the one hand it may be interesting to use miniaturize nanotransducers in biosensors (e.g. photonic transducer enabling both SPR and SERS thanks to nanostructuration) ; but on the other hand the transducers size reduction may prevent the targets to reach the biosensor’s active zone in a short time, because of mass transfer phenomena. Futhermore, when the sensing area is small by comparison with the other µAS zones, it targets are likely to get adsorbed on undesired surfaces. These targets are therefore lost and cannot contribute to the final, useful signal of the µAS. In these conditions the effectivity of the µAS can be questionned. Different ways are being explored to overcome such challenges, and may enable µAS for detection of low concentration targets. For instance, it is possible to perform selective chemical modifications of surfaces bearing different materials, in order to bind molecular probes only on the transducing zone, while repelling molecular targets from other material surfaces. We will show how it is possible to perform such orthogonal surfaces modifications with a submicronic spatial resolution, relying on self-assembly phenomena.

Proceedings Article | 1 March 2016 Paper

Label-free and fluorescence biosensing platform using one dimensional photonic crystal chips

F. Michelotti, S. Schmieder, A. Anopchenko, P. Munzert, A. Sinibaldi, R. Chandrawati, S. Rana, F. Sonntag, A. Occhicone, L. Napione, M. Stevens, E. Maillart, F.-E. Hibti, C. Frydman, N. Danz

Proceedings Volume 9750, 97501D (2016) https://doi.org/10.1117/12.2218517

KEYWORDS: Biosensing, Photonic crystals, Luminescence, Proteins, Surface plasmons, Waveguide sensors, Optical biosensors, Optical sensors, Biology, Electromagnetism, Ions, Charge-coupled devices, Signal detection, Sensors, Neodymium, Polymers, Fluorescent markers

Read Abstract +

Proceedings Article | 8 September 2004 Paper

Surface plasmon resonance imaging and versatile surface functionalization for real time comparisons of biochemical interactions

Emmanuel Maillart, Nathalie Bassil, Pierre Lecaruyer, Michael Canva, Yves Levy

Proceedings Volume 5461, (2004) https://doi.org/10.1117/12.554998

KEYWORDS: Reflectivity, Gold, Surface plasmons, Genetics, Sensors, Refractive index, Real time imaging, Signal detection, Metals, Plasmons

Read Abstract +

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Keywords/Phrases

Search In:

Publication Years