In the case of the medical lasers used for skin diseases and skin beauty, picosecond lasers with pulse durations of hundreds of picoseconds are mainly used. The picosecond laser breaks the pigment of the lesion into small pieces, enabling effective treatment without damaging the surrounding tissue. In the case, the beam profile is important because the laser must be uniformly irradiated to the desired area. In this paper, in order to obtain a uniform beam profile, the size of Nd:YAG Rod, which is a laser gain medium for each amplification stages, is different, and cap is used for the pre amplification stage. In addition, a beam shape compensator with an aspherical lens at the front of the handpiece was designed to realize a uniform beam in all handpieces.
High-energy ultrashort pulse lasers have been developed in a variety of applications such as medical treatment, defense, semiconductor and manufacturing. In terms of aesthetic dermatology, Alexandrite (Cr3+:BeAl2O4) lasers have an attractive and useful wavelength band (700 nm to approximately 800 nm). Therefore, Alexandrite lasers with shorter pulses and higher energy are required in the medical device market. Since alexandrite medium has a low energy gain at room temperature, it is not easy to make a flash-pumped picosecond alexandrite laser that produces sufficiently high output energy. To generate high-power picosecond laser pulses, we used self-injection and ultra short pulse generation techniques including Q-switching, mode-locking and cavity dumping. We have developed picosecond 755 nm alexandrite laser which can be operated at pulse width in the range from 600 to 2000 ps. A maximum average output energy of 400 mJ was achieved in the picosecond regime.
We developed a photoacoustic imaging (PAI) system based on a solid-state dye laser. Using the system, PA images of a tube filled with methylene blue (MB) below 3.9 cm chicken tissue were successfully obtained. After injecting MB into a rat, MB dyed sentinel lymph node (SLN) under chicken tissue was well described. In addition, it was confirmed the change in PA amplitude of the SLN over time in the PA images. Additionally, lymph vessels, SLN, and blood vessels were also successfully identified in multispectral PA images. These results demonstrate the clinical potential of the system in SLN detection.
Liposuction is one of the most common plastic surgery. Recently developed, a variety of technologies for lipolysis have been introduced to replace conventional liposuction. We have developed two types of laser lipolysis systems, which are non-invasive 1060 nm diode laser and minimally invasive laser system with 1980 nm and 2300 nm wavelengths. The developed laser lipolysis systems were used for preclinical experiments for a mini-pig. The thickness of the subcutaneous fat layer was measured by micro-CT, ultrasound and histopathology analysis. Our preclinical results showed that fat reduction was the most noticeable when using both non-invasive and invasive laser irradiation with combined all three laser wavelengths.
We have developed a lipolysis laser system that can be commercialized using wavelengths of 1980 nm and 2300 nm with excellent absorption in fat and water. An 808 nm laser diode and Nd:YVO4 were used to generate a 1064 nm wavelength light source, which is used as pumping light for nonlinear crystals. The oven was designed and fabricated to precisely control the temperature of the nonlinear crystal and applied to the mid-infrared lipolysis laser system. The characteristics of the developed laser were validated by measuring the change of the wavelength depending on the temperature and the output according to the wavelength. We analyzed fat reduction efficacy appears for two selected wavelengths.
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