Mr. Stephen Mead Profile

Stephen Mead

at Univ of Cambridge

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Profile Summary

Early diagnosis of precursor lesions that can lead to oesophageal or lung cancer is a key clinical unmet need. My interest is in developing endoscopic imaging tools that can provide sufficient contrast to track lesion progression. To meet this objective, I am working on multispectral systems that can measure optical absorption and scattering biomarkers.

Publications (4)

Proceedings Article | 16 March 2023 Presentation

Optical coherence elastography on clinical samples of gastric cancer shows promise for assessing alteration of mechanical properties with onset of disease (Conference Presentation)

Travis Sawyer, Graham Spicer, Stephen Mead, Massimiliano Di Pietro, Ashraf Sanduka, Tae Kim, Makenna Aitken, Faith Rice, Bhaskar Banerjee, Hemanth Gavini, Aws Alameri, Sarah Bohndiek, Jennifer Barton

Proceedings Volume PC12391, PC123910Y (2023) https://doi.org/10.1117/12.2652958

KEYWORDS: Cancer, Tissues, Elastography, Coherence (optics), Tissue optics, Tumors, Endoscopy, Visualization, Structural imaging, Standards development

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Proceedings Article | 6 March 2023 Presentation

Broadband hyperspectral imaging across visible and infrared biological windows using a single camera

Stephen Mead, Sarah Bohndiek, Calum Williams, Graham Spicer

Proceedings Volume PC12373, PC1237305 (2023) https://doi.org/10.1117/12.2649304

KEYWORDS: Cameras, Hyperspectral imaging, Visible radiation, Tissues, Infrared radiation, Infrared imaging, Infrared cameras, Cancer, Quantum efficiency, Tissue optics

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SPIE Journal Paper | 12 December 2022 Open Access

Multispectral imaging of nailfold capillaries using light-emitting diode illumination

Michaela Taylor-Williams, Stephen Mead, Travis Sawyer, Lina Hacker, Calum Williams, Michael Berks, Andrea Murray, Sarah Bohndiek

JBO, Vol. 27, Issue 12, 126002, (December 2022) https://doi.org/10.1117/12.10.1117/1.JBO.27.12.126002

KEYWORDS: Light emitting diodes, Capillaries, LED lighting, Oxygenation, Blood, Reflectivity, Multispectral imaging, Modeling, Imaging systems, Systems modeling

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Proceedings Article | 5 March 2021 Presentation

A low-cost LED-based multispectral capillaroscopy system for oximetry of the nailfold

Michaela Taylor-Williams, Steven Mead, Travis Sawyer, Lina Hacker, Calum Williams, Michael Berks, Andrea Murray, Sarah Bohndiek

Proceedings Volume 11651, 116510J (2021) https://doi.org/10.1117/12.2575869

KEYWORDS: Light emitting diodes, Oximetry, Capillaries, Visualization, Reflectivity, RGB color model, Modeling, Imaging systems, Hypoxia, Control systems

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