Prof. Vadim Backman Profile

Prof. Vadim Backman

Professor at Northwestern Univ

SPIE Involvement:

Conference Chair | Conference Program Committee | Author | Editor

Publications (62)

SPIE Journal Paper | 24 May 2024 Open Access

Deep learning-based spectroscopic single-molecule localization microscopy

Sunil Kumar Gaire, Ali Daneshkhah, Ethan Flowerday, Ruyi Gong, Jane Frederick, Vadim Backman

JBO, Vol. 29, Issue 06, 066501, (May 2024) https://doi.org/10.1117/12.10.1117/1.JBO.29.6.066501

KEYWORDS: Image restoration, Education and training, Point spread functions, Dyes, Biological imaging, Spectroscopy, Deep learning, Fluorescence imaging, Single molecule spectroscopy, Image processing

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Proceedings Article | 13 March 2024 Presentation

Characterizing spatial information of chromatin packing using the finite difference time domain (FDTD) method

Patrick Su, Vasundhara Agrawal, Nicolas Acosta, Wing Shun Li, Marcelo Carignano, Igal Szleifer, Vadim Backman

Proceedings Volume PC12856, PC1285607 (2024) https://doi.org/10.1117/12.3001756

KEYWORDS: Finite-difference time-domain method, Scanning transmission electron microscopy, Genetics, Biological imaging, Temporal resolution, Spectroscopy, Polymers, Organisms, Optical simulations, Optical imaging

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Proceedings Article | 13 March 2024 Presentation

Molecular specificity of nucleic acids via intrinsic stochastic fluorescence under visible light illumination

Ruyi Gong, Luay Almassalha, Vadim Backman

Proceedings Volume PC12849, PC128490A (2024) https://doi.org/10.1117/12.3001893

KEYWORDS: Fluorescence, Quantum DNA, Biological imaging, Visible radiation, Light sources and illumination, Super resolution, Quantum stochastic processes, Nucleic acids, Molecules, Stimulated emission depletion microscopy

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Proceedings Article | 13 March 2024 Presentation

Non-invasive measurement of optical properties in coral tissue and skeleton using Inverse spectroscopic optical coherence tomography (ISOCT)

Patrick Su, Graham L. Spicer, Aya Eid, James Winkelmann, Ji Yi, Luisa Marcelino, Vadim Backman, Michael Kuhl, Daniel Wangpraseurt, Kasper Brodersen, Erik Trampe

Proceedings Volume PC12856, PC128560B (2024) https://doi.org/10.1117/12.3001803

KEYWORDS: Optical coherence tomography, Tissues, Spectroscopy, Optical spectroscopy, Optical properties, Ocean optics, Tissue optics, Geometrical optics, Pigments, Light scattering

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Proceedings Article | 2 March 2022 Presentation + Paper

Application of machine learning algorithms for the classification of organs in premature infants using broadband optical spectroscopy

Ethan Flowerday, Ali Daneshkhah, Vadim Backman, Seth Goldstein

Proceedings Volume 11973, 1197303 (2022) https://doi.org/10.1117/12.2609659

KEYWORDS: Data modeling, Principal component analysis, Abdomen, Statistical analysis, Spectroscopy, Optical spectroscopy, Tissue optics, Feature selection, Performance modeling, Neural networks, Machine learning

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Proceedings Article | 2 March 2022 Presentation

Risk stratification of colorectal cancer using artificial intelligence based analysis of nanoscale chromatin modifications

Andrew Chang, Sravya Prabhala, Ali Daneshkhah, Hariharan Subramanian, Vadim Backman

Proceedings Volume PC11972, PC1197208 (2022) https://doi.org/10.1117/12.2608366

KEYWORDS: Colorectal cancer, Spectroscopy, Microscopy, Artificial intelligence, Feature extraction, Data modeling, Convolutional neural networks, Performance modeling, Optimization (mathematics), Imaging spectroscopy

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Proceedings Article | 10 March 2020 Presentation

Characterizing the refractive index auto-correlation function from whole cells using interferometric microscopy (Conference Presentation)

Aya Eid, Vadim Backman, Allen Taflove, Adam Eshein, Yue Li, Ranya Virk

Proceedings Volume 11253, 112530G (2020) https://doi.org/10.1117/12.2545053

KEYWORDS: Finite-difference time-domain method, Blood, Oxygen, Capillaries, Modeling, Tissues, Optical coherence tomography, Scattering, Molecules, Tumors

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Proceedings Article | 7 March 2019 Presentation

A data-quality-control protocol for in vivo oximetry in small vessels by visible light optical coherence tomography (Conference Presentation)

Rongrong Liu, Weiye Song, Vadim Backman, Ji Yi

Proceedings Volume 10867, 108670A (2019) https://doi.org/10.1117/12.2511171

KEYWORDS: In vivo imaging, Oximetry, Optical coherence tomography, Visible radiation, Oxygen, Capillaries, Cancer, Tissues, Data analysis, Hyperoxia

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Proceedings Article | 4 March 2019 Presentation

Spectral contrast optical coherence tomography angiography (Conference Presentation)

James Winkelmann, Graham Spicer, Aya Eid, Quyen Nguyen, Vadim Backman

Proceedings Volume 10867, 108671H (2019) https://doi.org/10.1117/12.2506664

KEYWORDS: Optical coherence tomography, Angiography, Visible radiation, Blood, Blood vessels, Doppler tomography, Speckle, Fourier transforms, Capillaries, Lymphatic system

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Proceedings Article | 4 March 2019 Presentation

Spectral based tissue classification and ultrastructural characterization using ISOCT (Conference Presentation)

Aya Eid, James Winkelmann, Graham Spicer, Luay Almassalha, Vadim Backman

Proceedings Volume 10888, 108880D (2019) https://doi.org/10.1117/12.2513825

KEYWORDS: Lymphatic system, Optical coherence tomography, Tissues, Blood, Tissue optics, Scattering, Visible radiation, Oxygen, In vivo imaging, Spectroscopy

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SPIE Journal Paper | 6 July 2018 Open Access

Fully automated fiber-based optical spectroscopy system for use in a clinical setting

Adam Eshein, Andrew Radosevich, Bradley Gould, Wenli Wu, Vani Konda, Leslie Yang, Ann Koons, Seth Feder, Vesta Valuckaite, Hemant Roy, Vadim Backman, The-Quyen Nguyen

JBO, Vol. 23, Issue 07, 075003, (July 2018) https://doi.org/10.1117/12.10.1117/1.JBO.23.7.075003

KEYWORDS: Calibration, In vivo imaging, Tissues, Optical spectroscopy, Tissue optics, Fiber optics, Spectroscopy, Reflectivity, Sensors, Optical transfer functions

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Proceedings Article | 15 March 2018 Presentation

Chromatin structure quantification from super-resolution intrinsic fluorescence imaging (Conference Presentation)

Yue Li, Biqin Dong, Adam Eshein, Graham Spicer, Wenli Wu, Luay Almassalha, Rongrong Liu, The-Quyen Nguyen, John Chandler, Cheng Sun, Hao Zhang, Vadim Backman

Proceedings Volume 10504, 1050407 (2018) https://doi.org/10.1117/12.2289106

KEYWORDS: Fractal analysis, Super resolution, Luminescence, Photonic microstructures, Microscopy, Algorithm development, Visible radiation, Photonic nanostructures, Ovarian cancer, Transmission electron microscopy

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Proceedings Article | 14 March 2018 Presentation

Multimodal nanoscale imaging of chromatin with super resolution microscopy and partial wave spectroscopy (Conference Presentation)

Adam Eshein, Xiang Zhou, Luay Almassalha, Scott Gladstein, Yue Li, The-Quyen Nguyen, John Chandler, Graham Spicer, Cheng Sun, Hao Zhang, Vadim Backman

Proceedings Volume 10497, 104970V (2018) https://doi.org/10.1117/12.2291306

KEYWORDS: Imaging spectroscopy, Multimodal imaging, Spectroscopy, Super resolution, Microscopy, Fluorescence spectroscopy, Photonic microstructures, Spectroscopes, Visualization, Polymers

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Proceedings Article | 14 March 2018 Presentation

Three-dimensional, polarization-sensitive, spectroscopic photon localization microscopy for parallel single-molecules imaging and tracking (Conference Presentation)

Biqin Dong, Brian Soetikno, Xiangfan Chen, Vadim Backman, Cheng Sun, Hao Zhang

Proceedings Volume 10500, 1050009 (2018) https://doi.org/10.1117/12.2291235

KEYWORDS: Imaging spectroscopy, Spectroscopy, Polarization, Photon polarization, Photonic microstructures, Microscopy, Super resolution microscopy, 3D acquisition, Imaging systems, Luminescence

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