Mr. Saeed Boorboor Profile

Saeed Boorboor

at Stony Brook Univ

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Proceedings Article | 6 March 2018 Paper

Crowdsourcing lung nodules detection and annotation

Saeed Boorboor, Saad Nadeem, Ji Hwan Park, Kevin Baker, Arie Kaufman

Proceedings Volume 10579, 105791D (2018) https://doi.org/10.1117/12.2292563

KEYWORDS: Lung, Video, Computed tomography, Lung cancer, Chest, Computer aided diagnosis and therapy, Visualization, 3D modeling, Computer-aided diagnosis

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We present crowdsourcing as an additional modality to aid radiologists in the diagnosis of lung cancer from clinical chest computed tomography (CT) scans. More specifically, a complete work flow is introduced which can help maximize the sensitivity of lung nodule detection by utilizing the collective intelligence of the crowd. We combine the concept of overlapping thin-slab maximum intensity projections (TS-MIPs) and cine viewing to render short videos that can be outsourced as an annotation task to the crowd. These videos are generated by linearly interpolating overlapping TS-MIPs of CT slices through the depth of each quadrant of a patient's lung. The resultant videos are outsourced to an online community of non-expert users who, after a brief tutorial, annotate suspected nodules in these video segments. Using our crowdsourcing work flow, we achieved a lung nodule detection sensitivity of over 90% for 20 patient CT datasets (containing 178 lung nodules with sizes between 1-30mm), and only 47 false positives from a total of 1021 annotations on nodules of all sizes (96% sensitivity for nodules>4mm). These results show that crowdsourcing can be a robust and scalable modality to aid radiologists in screening for lung cancer, directly or in combination with computer-aided detection (CAD) algorithms. For CAD algorithms, the presented work flow can provide highly accurate training data to overcome the high false-positive rate (per scan) problem. We also provide, for the first time, analysis on nodule size and position which can help improve CAD algorithms.

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